Florinef 0.1 Mg Tablets 0.1 mg Tablets.
Clinical Summary
Quick overview from the medicine insert
Indication
Partial replacement therapy for primary adrenocortical insufficiency and treatment of salt-losing adrenogenital syndrome.
Dosage (summary)
Adults: 0.1 mg to 0.2 mg daily; Children: 0.05 mg to 0.1 mg daily.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation due to teratogenicity; breastfeeding not recommended.
Key Drug Interactions
- Potassium-depleting agents
- Anticoagulants
- Antidiabetics
- NSAIDs
Contraindications
- Hypersensitivity
- Systemic infections
- Uncontrolled congestive heart failure
- Active peptic ulcer
Common side effects
- Hypertension
- Hypokalaemia
- Weight gain
- Mood changes
Counselling Points
- Monitor blood pressure and electrolytes regularly.
- Avoid live vaccines during therapy.
- Report any mood changes or signs of infection.
Serious warnings
- Risk of adrenal insufficiency on withdrawal
- Increased susceptibility to infections
- Potential for severe psychiatric reactions
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