Fosaprepitant Cipla 150 mg Lyophilised powder for Solution for Infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of nausea and vomiting associated with highly and moderately emetogenic cancer chemotherapy.
Dosage (summary)
150 mg IV on Day 1, no further doses.
Onset of Action / Duration
Onset: 30 mins, Duration: Not specified.
Special Populations
- Elderly
- Severe hepatic insufficiency
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- Warfarin
- Hormonal contraceptives
Contraindications
- Hypersensitivity to ingredients
- Pregnancy
- Breastfeeding
- Co-administration with pimozide, terfenadine, astemizole, cisapride
Common side effects
- Hiccups
- Fatigue
- Headache
- Constipation
- Dyspepsia
Counselling Points
- Monitor INR if on warfarin
- Use alternative contraception during and 28 days after treatment
- Do not drive if experiencing dizziness
Serious warnings
- Hypersensitivity reactions
- Severe hepatic insufficiency caution
- Infusion site reactions
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