Easan 150 mg Powder for solution for infusion

Easan 150 mg Powder for solution for infusion

S4
PDF Leaflet Revision Date: 7 March 2023


Clinical Summary

Quick overview from the medicine insert

Indication

Prevention of nausea and vomiting associated with cancer chemotherapy.

Dosage (summary)

150 mg IV on Day 1, no adjustment for elderly or renal impairment.

Onset of Action / Duration

Onset: 30 mins, Duration: Not specified.

Special Populations

  • Moderate hepatic impairment
  • Severe hepatic impairment
  • Renal impairment

Pregnancy & Breastfeeding

Not recommended in pregnancy; breastfeeding not advised.

Key Drug Interactions

  • CYP3A4 inhibitors
  • CYP3A4 inducers
  • Warfarin

Contraindications

  • Hypersensitivity to aprepitant
  • Co-administration with pimozide
  • Pregnancy
  • Breastfeeding
  • Paediatric patients

Common side effects

  • Fatigue
  • Headache
  • Constipation
  • Dyspepsia
  • Hiccups

Counselling Points

  • Monitor for hypersensitivity
  • Use non-hormonal contraception
  • Avoid in pregnancy and breastfeeding

Serious warnings

  • Hypersensitivity reactions
  • Infusion site reactions
  • Caution in hepatic impairment
Important Disclaimer

The Easan 150 mg Powder for solution for infusion professional information leaflet below is the property of Kahma Biotech and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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