Fripnit 300 mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of latent tuberculosis infection in high-risk patients.
Dosage (summary)
Once weekly for 12 weeks, max 900 mg based on weight.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; safety in lactation not established.
Key Drug Interactions
- CYP3A4 inducers/inhibitors
- Hormonal contraceptives
- Digoxin
Contraindications
- Hypersensitivity to rifapentine
- Porphyria
- Liver disease
Common side effects
- Hypersensitivity
- Nausea
- Headache
- Hepatitis
Counselling Points
- Take with food
- Monitor for liver function
- May discolor body fluids
Serious warnings
- Hepatotoxicity
- Severe cutaneous adverse reactions
- Clostridium difficile-associated diarrhea
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