Fripnit 300 mg Tablet

Fripnit 300 mg Tablet

S4
PDF Leaflet Revision Date: 24 March 2023

API: Rifapentine | Company: Pharma Dynamics

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of latent tuberculosis infection in high-risk patients.

Dosage (summary)

Once weekly for 12 weeks, max 900 mg based on weight.

Special Populations

  • Elderly
  • Hepatic impairment
  • Renal impairment

Pregnancy & Breastfeeding

Not recommended in pregnancy; safety in lactation not established.

Key Drug Interactions

  • CYP3A4 inducers/inhibitors
  • Hormonal contraceptives
  • Digoxin

Contraindications

  • Hypersensitivity to rifapentine
  • Porphyria
  • Liver disease

Common side effects

  • Hypersensitivity
  • Nausea
  • Headache
  • Hepatitis

Counselling Points

  • Take with food
  • Monitor for liver function
  • May discolor body fluids

Serious warnings

  • Hepatotoxicity
  • Severe cutaneous adverse reactions
  • Clostridium difficile-associated diarrhea
Important Disclaimer

The Fripnit 300 mg Tablet professional information leaflet below is the property of Pharma Dynamics and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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