Glucovance 1.25mg. 250mg Tablet

Glucovance 1.25mg. 250mg Tablet

S3
PDF Leaflet Revision Date: 23 July 2010

API: Glibenclamide Metformin | Company: Merck

Clinical Summary

Quick overview from the medicine insert

Indication

Type 2 diabetes management as initial or second-line therapy.

Dosage (summary)

Start with 1 tablet of Glucovance 250 mg/1.25 mg daily; adjust based on response.

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Not recommended during pregnancy or lactation.

Key Drug Interactions

  • Miconazole
  • Fluconazole
  • Phenylbutazone
  • Diuretics
  • ACE-inhibitors

Contraindications

  • Hypersensitivity to components
  • Type 1 diabetes
  • Renal disease
  • Liver disease
  • Acute alcohol intoxication

Common side effects

  • Hypoglycaemia
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain

Counselling Points

  • Take with meals
  • Monitor blood glucose regularly
  • Avoid alcohol
  • Recognize hypoglycaemia symptoms

Serious warnings

  • Lactic acidosis
  • Risk of cardiovascular mortality
  • Hypoglycaemia symptoms
Important Disclaimer

The Glucovance 1.25mg. 250mg Tablet professional information leaflet below is the property of Merck and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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