Glucovance 1.25mg. 250mg Tablet

    Glucovance 1.25mg. 250mg Tablet

    S3
    PDF Leaflet Revision Date: 23 July 2010

    API: Glibenclamide Metformin | Company: Merck

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Type 2 diabetes management as initial or second-line therapy.

    Dosage (summary)

    Start with 1 tablet of Glucovance 250 mg/1.25 mg daily; adjust based on response.

    Special Populations

    • Elderly
    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Not recommended during pregnancy or lactation.

    Key Drug Interactions

    • Miconazole
    • Fluconazole
    • Phenylbutazone
    • Diuretics
    • ACE-inhibitors

    Contraindications

    • Hypersensitivity to components
    • Type 1 diabetes
    • Renal disease
    • Liver disease
    • Acute alcohol intoxication

    Common side effects

    • Hypoglycaemia
    • Nausea
    • Vomiting
    • Diarrhoea
    • Abdominal pain

    Counselling Points

    • Take with meals
    • Monitor blood glucose regularly
    • Avoid alcohol
    • Recognize hypoglycaemia symptoms

    Serious warnings

    • Lactic acidosis
    • Risk of cardiovascular mortality
    • Hypoglycaemia symptoms
    Important Disclaimer

    The Glucovance 1.25mg. 250mg Tablet professional information leaflet below is the property of Merck and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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