Glusita Plus 50/500 Mg, Glusita Plus 50/850 Mg & Glusita Plus 50/1000 Mg 50 mg, 500 mg, 850 mg, 1000 mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunct to diet and exercise for glycaemic control in type 2 diabetes.
Dosage (summary)
Starting dose based on current regimen, generally 50 mg sitagliptin/500 mg metformin twice daily with meals.
Special Populations
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- Alcohol increases risk of lactic acidosis
- Iodinated contrast materials
Contraindications
- Hypersensitivity to components
- Renal disease
- Acute metabolic acidosis
- Diabetic pre-coma
- Hepatic impairment
- Breastfeeding
Common side effects
- Hypoglycaemia
- Nausea
- Diarrhoea
- Lactic acidosis
- Pancreatitis
Counselling Points
- Monitor for signs of pancreatitis
- Avoid excessive alcohol intake
- Regular renal function monitoring
Serious warnings
- Risk of lactic acidosis
- Acute pancreatitis
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