Josisitin Plus 50/500 Mg Josisitin Plus 50/850 Mg & Josisitin Plus 50/1000 Mg 50 mg, 500 mg, 850 mg, 1000 mg Tablet
PDF Leaflet Revision Date: 28 February 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunct to diet and exercise for glycaemic control in type 2 diabetes.
Dosage (summary)
50 mg sitagliptin/500 mg metformin twice daily with meals; adjust based on current regimen.
Special Populations
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- Alcohol increases risk of lactic acidosis
- Iodinated contrast materials
Contraindications
- Hypersensitivity to components
- Renal disease
- Acute metabolic acidosis
- Diabetic pre-coma
- Hepatic impairment
- Breastfeeding
Common side effects
- Hypoglycaemia
- Nausea
- Diarrhoea
- Lactic acidosis
Counselling Points
- Monitor for signs of pancreatitis
- Avoid excessive alcohol intake
- Regular renal function monitoring
Serious warnings
- Risk of acute pancreatitis
- Lactic acidosis risk in renal impairment
Important Disclaimer
The Josisitin Plus 50/500 Mg Josisitin Plus 50/850 Mg & Josisitin Plus 50/1000 Mg 50 mg, 500 mg, 850 mg, 1000 mg Tablet professional information leaflet below is the property of Sandoz Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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