Inozi-Co 300mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of active tuberculosis in high-risk adults and children.
Dosage (summary)
Adults/children u226512 years: 900 mg once weekly for 12 weeks; Children 2-11 years: weight-based dosing up to 900 mg.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; contraindicated in breastfeeding.
Key Drug Interactions
- Protease inhibitors
- NNRTIs
- Hormonal contraceptives
Contraindications
- Hypersensitivity to isoniazid/rifapentine
- Acute/chronic liver disease
- Severe renal failure
- Alcoholism
- Seizure disorders
Common side effects
- Nausea
- Headache
- Fatigue
- Skin reactions
Counselling Points
- Take with food
- Adhere to treatment regimen
- Monitor for liver function
- Avoid alcohol
Serious warnings
- Hepatotoxicity
- Hypersensitivity reactions
- Severe cutaneous adverse reactions
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