Keppra Tabs 250mg. 500mg. 750mg. 1000mg Tablets

Keppra Tabs 250mg. 500mg. 750mg. 1000mg Tablets

S3
PDF Leaflet Revision Date: 11 Oct 2013


Clinical Summary

Quick overview from the medicine insert

Indication

Monotherapy and adjunctive therapy for seizures.

Dosage (summary)

Adults: Start at 250 mg twice daily, max 1500 mg. Adjust for renal impairment.

Onset of Action / Duration

Onset: 1.3 hours, Duration: 7u00b11 hours

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy and lactation.

Key Drug Interactions

  • Probenecid may inhibit renal clearance of metabolite.
  • No significant interactions with other antiepileptics.

Contraindications

  • Hypersensitivity to levetiracetam or excipients.
  • Pregnancy
  • Lactation

Common side effects

  • Somnolence
  • Dizziness
  • Asthenia

Counselling Points

  • Report any mood changes or suicidal thoughts.
  • Avoid abrupt discontinuation.
  • Caution when driving or operating machinery.

Serious warnings

  • Gradual discontinuation recommended.
  • Risk of increased seizure frequency.
  • Suicidal ideation reported.
Important Disclaimer

The Keppra Tabs 250mg. 500mg. 750mg. 1000mg Tablets professional information leaflet below is the property of Glaxosmithkline South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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