Kivexa 600mg. 300mg Tablet

Kivexa 600mg. 300mg Tablet

S4
PDF Leaflet Revision Date: 05 August 2019

API: Abacavir, Lamivudine | Company: Gsk

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of HIV infection in adults and adolescents from 12 years of age, weighing at least 40 kg.

Dosage (summary)

One tablet once daily for adults and adolescents weighing at least 40 kg.

Special Populations

  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Not recommended during pregnancy or breastfeeding due to potential risks.

Key Drug Interactions

  • Ethanol may increase abacavir levels.
  • Trimethoprim increases lamivudine exposure.

Contraindications

  • Hypersensitivity to abacavir or lamivudine.
  • Moderate and severe hepatic impairment.
  • Children below 12 years or weighing less than 40 kg.

Common side effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Rash
  • Fever
  • Fatigue

Counselling Points

  • Inform patients about hypersensitivity risks.
  • Advise against restarting KIVEXA after hypersensitivity.
  • Encourage patients to report any symptoms immediately.

Serious warnings

  • Risk of life-threatening hypersensitivity reactions.
  • Lactic acidosis and severe hepatomegaly.
  • Pancreatitis risk.
Important Disclaimer

The Kivexa 600mg. 300mg Tablet professional information leaflet below is the property of Gsk and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

Healthcare Professionals Only

This content is for registered healthcare professionals

Sign in or create a free account to read the full package insert.

Free for HPCSA-registered professionals. Powered by Medinsert.

Successfully Stashed! 💊

This package insert has been safely stored in your digital medical cabinet. No prescription needed to view it later!

View My Favourites