Lopimune 40 mg and 10 mg CAPSULE (ORAL PELLETS)
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 infection in combination with other antiretrovirals.
Dosage (summary)
Adults: 400/100 mg twice daily; Children: weight-based dosing.
Special Populations
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; avoid breastfeeding.
Key Drug Interactions
- CYP3A4 substrates
- Rifampicin
- Colchicine
- PDE5 inhibitors
Contraindications
- Severe hepatic insufficiency
- Hypersensitivity to components
Common side effects
- Diarrhoea
- Nausea
- Vomiting
- Dyslipidaemia
Counselling Points
- Take with food
- Do not chew or crush pellets
- Monitor for liver function abnormalities
Serious warnings
- Risk of pancreatitis
- Increased bleeding in haemophilia
- Immune reactivation syndrome
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