Lopinavir And Ritonavir Cipla 40 mg and 10 mg ORAL PELLETS

Lopinavir And Ritonavir Cipla 40 mg and 10 mg ORAL PELLETS

S4
PDF Leaflet Revision Date: 26 June 2019

API: Lopinavir, Ritonavir | Company: Cipla Medpro

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of HIV infection in combination with other antiretroviral medicines.

Dosage (summary)

Adults: 400/100 mg twice daily with food. Children: Dosing varies by weight.

Special Populations

  • Hepatic impairment
  • Renal impairment

Pregnancy & Breastfeeding

Not recommended during pregnancy; avoid breastfeeding to prevent HIV transmission.

Key Drug Interactions

  • CYP3A inhibitors
  • CYP3A inducers
  • Colchicine
  • Rifampin

Contraindications

  • Hypersensitivity to lopinavir or ritonavir
  • Severe hepatic insufficiency

Common side effects

  • Diarrhea
  • Nausea
  • Headache
  • Fatigue
  • Hyperlipidemia

Counselling Points

  • Take with food
  • Do not alter dose without consulting a doctor
  • Monitor for signs of pancreatitis or liver dysfunction

Serious warnings

  • Risk of pancreatitis
  • Hepatotoxicity
  • QT interval prolongation
Important Disclaimer

The Lopinavir And Ritonavir Cipla 40 mg and 10 mg ORAL PELLETS professional information leaflet below is the property of Cipla Medpro and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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