Macaine Hcl 0,5 % Injection With Adrenaline 1 mL Injection
PDF Leaflet Revision Date: 11 August 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Peripheral nerve block, caudal or epidural block.
Dosage (summary)
Varies by procedure; max 150 mg per injection.
Onset of Action / Duration
Onset: Rapid, Duration: Several hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established for use in pregnancy; caution in breastfeeding.
Key Drug Interactions
- Antidysrhythmics
- Beta blockers
- Halogenated anesthetics
Contraindications
- Sensitivity to bupivacaine/adrenaline
- IV regional anesthesia
- Severe heart disease
Common side effects
- Dizziness
- Hypotension
- Urinary retention
- Nausea
Counselling Points
- Avoid driving for 2-4 hours post-procedure
- Report any unusual symptoms
- Stay hydrated before procedure
Serious warnings
- Risk of systemic toxicity
- Monitor for overdose
- Caution in patients with cardiovascular disease
Important Disclaimer
The Macaine Hcl 0,5 % Injection With Adrenaline 1 mL Injection professional information leaflet below is the property of Adcock Ingram Critical Care and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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