Macleods Nevirapine 200 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
For treatment of HIV-1 infection in combination with other antiretroviral agents.
Dosage (summary)
200 mg once daily for 14 days, then 200 mg twice daily.
Special Populations
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in breastfeeding; single dose may be used during labor.
Key Drug Interactions
- CYP3A inducers
- CYP2B inducers
- Fluconazole
- Warfarin
Contraindications
- Hypersensitivity to nevirapine
- Severe hepatic dysfunction
- End-stage renal failure
Common side effects
- Rash
- Hepatitis
- Nausea
- Headache
Counselling Points
- Report any rash immediately
- Avoid hormonal contraceptives alone
- Monitor for signs of hepatitis
Serious warnings
- Severe skin reactions
- Hepatotoxicity
- Monitor liver function
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