Metplitin Co 50/850, 50/1000 50 mg/850 mg, 50 mg/1000 mg Tablet
PDF Leaflet Revision Date: 01 October 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunct to diet and exercise for type 2 diabetes control.
Dosage (summary)
50 mg sitagliptin/850 mg metformin or 50 mg sitagliptin/1000 mg metformin, twice daily with meals.
Special Populations
- Renal impairment
- Elderly
- Paediatric population
Pregnancy & Breastfeeding
Not recommended in pregnancy or breastfeeding.
Key Drug Interactions
- Alcohol increases lactic acidosis risk
- Iodinated contrast agents
Contraindications
- Hypersensitivity to components
- Severe renal failure (GFR < 30 mL/min)
- Acute metabolic acidosis
- Hepatic impairment
- Breastfeeding
Common side effects
- Hypoglycaemia
- Nausea
- Vomiting
- Flatulence
- Diarrhoea
Counselling Points
- Monitor blood glucose regularly
- Report severe abdominal pain immediately
- Avoid excessive alcohol intake
Serious warnings
- Risk of acute pancreatitis
- Lactic acidosis risk in renal impairment
Important Disclaimer
The Metplitin Co 50/850, 50/1000 50 mg/850 mg, 50 mg/1000 mg Tablet professional information leaflet below is the property of Dr ReddyãS Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
