Molipaxin 50mg. 100mg Capsule
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression and mixed anxiety and depression.
Dosage (summary)
Adults: 150 mg/day initially, increase to 300-400 mg/day; elderly: start at 100 mg/day.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; contraindicated in breastfeeding.
Key Drug Interactions
- Alcohol
- CYP3A4 inhibitors
- Tricyclic antidepressants
Contraindications
- Hypersensitivity to trazodone
- MAOIs
- Alcohol intoxication
- Acute myocardial infarction
Common side effects
- Drowsiness
- Dizziness
- Nausea
- Dry mouth
Counselling Points
- Avoid alcohol
- Monitor for suicidal thoughts
- Do not operate machinery if drowsy
Serious warnings
- Increased risk of suicidal thoughts
- Severe hepatic disorders
- QT interval prolongation
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