Navalpro Cr 200 mg/300 mg/500 mg Film-Coated Tablets
PDF Leaflet Revision Date: 31 July 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of epilepsy and manic episodes in bipolar disorder.
Dosage (summary)
Start at 600 mg/day, increase by 200 mg every 3 days; maintenance 1000-2000 mg/day.
Special Populations
- Elderly
- Renal impairment
- Paediatric population
Pregnancy & Breastfeeding
High teratogenic potential; contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Antipsychotics
- MAO inhibitors
- Benzodiazepines
- Carbapenem antibiotics
Contraindications
- Hypersensitivity
- Liver disease
- Mitochondrial disorders
- Urea cycle disorders
Common side effects
- Nausea
- Vomiting
- Dizziness
- Somnolence
- Weight gain
Counselling Points
- Take with food
- Avoid alcohol
- Monitor for signs of liver dysfunction
- Use effective contraception in women of childbearing potential
Serious warnings
- Severe liver damage
- Pancreatitis
- Suicidal ideation
- Aggravated convulsions
Important Disclaimer
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Clinical Particulars
Section 4 of the official insert — extracted exactly as issued, no alterations
