Nexiam 20 Mg; Nexiam 40 Mg Gastric Resistant Tablets Nexiam 10 Mg Sachets (Granules) 20mg, 40mg, 10mg Tablets, granules
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of Gastro-oesophageal Reflux Disease (GORD) and prevention of NSAID-related ulcers.
Dosage (summary)
20 mg once daily for GORD; 40 mg once daily for erosive reflux oesophagitis.
Onset of Action / Duration
Onset: 1 hour, Duration: 24 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety not established during pregnancy and lactation.
Key Drug Interactions
- Clopidogrel
- Warfarin
- Atazanavir
- Nelfinavir
Contraindications
- Hypersensitivity to esomeprazole or benzimidazoles
- Concomitant use with atazanavir or nelfinavir
Common side effects
- Headache
- Abdominal pain
- Diarrhoea
- Nausea
Counselling Points
- Take tablets whole, do not chew or crush.
- Monitor for gastrointestinal symptoms.
- Avoid alcohol and NSAIDs.
Serious warnings
- May mask symptoms of gastric malignancy
- Increased risk of gastrointestinal infections
The Nexiam 20 Mg; Nexiam 40 Mg Gastric Resistant Tablets Nexiam 10 Mg Sachets (Granules) 20mg, 40mg, 10mg Tablets, granules professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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