Ozurdex 700 _g per implan Intravitreal implant in applicator
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of visual impairment due to DME, macular oedema from BRVO/CRVO, and non-infectious uveitis.
Dosage (summary)
One implant administered intra-vitreally; retreatment after ~6 months if needed.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding due to potential risks.
Key Drug Interactions
- CYP450 3A4 inhibitors may increase corticosteroid effects
- Caution with anticoagulants and anti-platelets
Contraindications
- Hypersensitivity to dexamethasone
- Active ocular infections
- Uncontrolled glaucoma
- Aphakic eyes with posterior capsule rupture
Common side effects
- Increased intraocular pressure
- Cataract
- Conjunctival haemorrhage
- Visual disturbance
Counselling Points
- Monitor for signs of infection
- Report visual changes immediately
- Avoid driving until vision stabilizes
Serious warnings
- Risk of endophthalmitis
- Increased intraocular pressure
- Potential for implant migration
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