Paclitaxel Fresenius 30mg / 5ml. 100mg / 5ml. 300mg / 50ml Infusion

Paclitaxel Fresenius 30mg / 5ml. 100mg / 5ml. 300mg / 50ml Infusion

S4
PDF Leaflet Revision Date: 3 May 2018

API: Paclitaxel | Company: Fresenius Kabi

Clinical Summary

Quick overview from the medicine insert

Indication

Palliative treatment of advanced ovarian, breast, and non-small cell lung cancer.

Dosage (summary)

135-175 mg/mu00b2 IV over 3-24 hours every 3 weeks, pre-medicate before administration.

Special Populations

  • Hepatic impairment
  • Elderly

Pregnancy & Breastfeeding

Contraindicated in pregnancy and lactation; may cause fetal harm.

Key Drug Interactions

  • Caution with ketoconazole
  • Increased doxorubicin levels when combined

Contraindications

  • Severe hypersensitivity to paclitaxel
  • Baseline neutrophils <1500/mmu00b3
  • Pregnancy and lactation

Common side effects

  • Neutropenia
  • Peripheral neuropathy
  • Hypersensitivity reactions
  • Nausea
  • Vomiting

Counselling Points

  • Avoid pregnancy during treatment
  • Monitor for signs of infection
  • Do not drive if experiencing dizziness

Serious warnings

  • Severe hypersensitivity reactions
  • Bone marrow suppression
  • Cardiovascular events
Important Disclaimer

The Paclitaxel Fresenius 30mg / 5ml. 100mg / 5ml. 300mg / 50ml Infusion professional information leaflet below is the property of Fresenius Kabi and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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