Taxol 30mg / 5ml. 100mg / 5ml. 300mg / 50ml Infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Palliative treatment of advanced ovarian, breast, and lung cancers.
Dosage (summary)
175 mg/mu00b2 IV over 3 hours every 3 weeks; adjust for neutrophil count.
Special Populations
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy; avoid breastfeeding during therapy.
Key Drug Interactions
- Ketoconazole may inhibit metabolism
- Increased doxorubicin levels when combined
Contraindications
- Severe hypersensitivity to TAXOL
- Neutrophils < 1500/mmu00b3
Common side effects
- Neutropenia
- Peripheral neuropathy
- Hypersensitivity reactions
- Nausea
- Vomiting
Counselling Points
- Premedicate with corticosteroids and antihistamines
- Monitor for hypersensitivity reactions
- Avoid pregnancy during treatment
Serious warnings
- Severe hypersensitivity reactions possible
- Bone marrow suppression
- Cardiac conduction abnormalities
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