Pexola 0.125mg / 0.25mg / 1.0mg Tablets
PDF Leaflet Revision Date: 19 April 2013
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of idiopathic Parkinsonu2019s disease and Restless Legs Syndrome.
Dosage (summary)
Parkinson's: Start at 0.375 mg/day, max 4.5 mg/day. RLS: Start at 0.125 mg once daily, max 0.75 mg/day.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; inhibits lactation.
Key Drug Interactions
- Cimetidine increases AUC by 50%
- Dopamine antagonists may reduce effectiveness
Contraindications
- Hypersensitivity to pramipexole
- Severe renal impairment
- Children under 18
Common side effects
- Somnolence
- Dizziness
- Nausea
- Hallucinations
Counselling Points
- Monitor for drowsiness
- Avoid driving if drowsy
- Report abnormal behaviors
Serious warnings
- Risk of falling asleep during activities
- Impulse control disorders
Important Disclaimer
The Pexola 0.125mg / 0.25mg / 1.0mg Tablets professional information leaflet below is the property of Boehringer Ingelheim and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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