Phenylephrine Hydrochloride Injection 10 mg/mL Solution for injection.
Clinical Summary
Quick overview from the medicine insert
Indication
For increasing blood pressure in adults with hypotension from vasodilation.
Dosage (summary)
Dilute before administration; 50-250 mcg IV bolus or 0.5-6 mcg/kg/min continuous infusion.
Onset of Action / Duration
Onset: minutes, Duration: short-lived
Special Populations
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; small amounts excreted in breast milk.
Key Drug Interactions
- Non-selective MAO inhibitors
- Dopaminergic agents
- Tricyclic antidepressants
Contraindications
- Hypersensitivity
- Uncontrolled hypertension
- Severe cardiac failure
Common side effects
- Bradycardia
- Hypertension
- Nausea
- Vomiting
Counselling Points
- Monitor for side effects
- Avoid extravasation
- Gradually reduce dosage when discontinuing
Serious warnings
- Risk of ischemic gangrene
- Monitor blood pressure
- Caution in patients with coronary artery disease
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