Propofol 1 % Ps Fresenius 10 mg per mL Emulsion for injection or infusion in pre-filled syringe
PDF Leaflet Revision Date: 30 January 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Short-acting intravenous general anaesthetic.
Dosage (summary)
Induction: 1.5-2.5 mg/kg; Maintenance: 4-12 mg/kg/h.
Onset of Action / Duration
Onset: 30 secs, Duration: varies.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
- Obesity
Pregnancy & Breastfeeding
Contraindicated in pregnancy; avoid breastfeeding for 24 hours post-administration.
Key Drug Interactions
- CNS depressants
- Opioids
- Benzodiazepines
Contraindications
- Hypersensitivity to propofol
- Children <3 years
- Severe cardiac failure
Common side effects
- Hypotension
- Transient apnoea
- Nausea
- Bradycardia
Counselling Points
- Avoid driving for 12 hours
- Do not consume alcohol for 24 hours
- Monitor for respiratory depression.
Serious warnings
- Respiratory depression
- Anaphylaxis risk
- Propofol infusion syndrome
Important Disclaimer
The Propofol 1 % Ps Fresenius 10 mg per mL Emulsion for injection or infusion in pre-filled syringe professional information leaflet below is the property of Fresenius Kabi South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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