Prostin Vr 0,5 mg/mL Sterile solution for infusion.
PDF Leaflet Revision Date: 07 August 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Palliative therapy to maintain ductus arteriosus patency in neonates with congenital heart defects.
Dosage (summary)
Start at 0.1 mcg/kg/min, adjust to lowest effective dose.
Special Populations
- Neonates
- Patients with bleeding tendencies
Key Drug Interactions
- Co-administration with propylene glycol or alcohol may increase ethanol effects
Contraindications
- Respiratory distress syndrome
Common side effects
- Flushing
- Bradycardia
- Hypotension
- Apnoea
Counselling Points
- Administer only in facilities with pediatric intensive care
- Monitor for signs of overdose
Serious warnings
- Monitor for antral hyperplasia and gastric outlet obstruction with long-term use
Important Disclaimer
The Prostin Vr 0,5 mg/mL Sterile solution for infusion. professional information leaflet below is the property of Pfizer Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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