Pyrocaps Capsule 20 mg Capsules
Clinical Summary
Quick overview from the medicine insert
Indication
For anti-inflammatory and analgesic activity in conditions like rheumatoid arthritis and acute gout.
Dosage (summary)
20mg daily for rheumatoid arthritis; 40mg for 2 days for acute musculoskeletal disorders, then 20mg; 40mg for acute gout.
Onset of Action / Duration
Onset: 7-10 days, Duration: 24 hours
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Not recommended in late pregnancy; may cause fetal renal dysfunction. Safety in lactation not established.
Key Drug Interactions
- Anticoagulants
- Other NSAIDs
- Methotrexate
- Lithium
Contraindications
- Hypersensitivity to piroxicam
- Active peptic ulcer
- Severe heart failure
- Last trimester of pregnancy
Common side effects
- Gastrointestinal bleeding
- Dizziness
- Headache
- Skin rash
Counselling Points
- Take with food to minimize GI upset
- Report any unusual abdominal symptoms
- Avoid use in pregnancy unless advised
Serious warnings
- Risk of serious gastrointestinal events
- Skin reactions like SJS and TEN
- Cardiovascular risks
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