Ran-Perindopril 4 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of hypertension and congestive heart failure.
Dosage (summary)
Initial 4 mg daily, may increase to 8 mg based on response.
Onset of Action / Duration
Onset: 4-6 hours, Duration: 24 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; safety in lactation not established.
Key Drug Interactions
- Potassium-sparing diuretics
- Lithium
- Aliskiren
- Fluoroquinolones
Contraindications
- Hypersensitivity to perindopril
- History of angioedema
- Severe renal impairment
- Bilateral renal artery stenosis
Common side effects
- Dizziness
- Cough
- Hypotension
- Hyperkalaemia
Counselling Points
- Take in the morning before breakfast
- Monitor blood pressure regularly
- Report any signs of angioedema immediately
Serious warnings
- Risk of angioedema
- Symptomatic hypotension
- Renal impairment
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