Raypare 40 mg Powder for solution for injection (powder for injection).

Raypare 40 mg Powder for solution for injection (powder for injection).

S3
PDF Leaflet Revision Date: 09 September 2025

API: Parecoxib | Company: Abex Pharmaceutica

Clinical Summary

Quick overview from the medicine insert

Indication

Short-term management of post-operative pain.

Dosage (summary)

Initial 40 mg IV/IM, then 20-40 mg every 6-12 hours, max 80 mg/day.

Onset of Action / Duration

Onset: 7-14 mins, Duration: 7+ hours.

Special Populations

  • Elderly
  • Hepatic impairment
  • Renal impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy and lactation.

Key Drug Interactions

  • Fluconazole
  • Warfarin
  • ACE inhibitors
  • Diuretics

Contraindications

  • Hypersensitivity to parecoxib
  • Severe hepatic impairment
  • Severe renal impairment
  • History of gastrointestinal bleeding
  • Coronary artery bypass surgery

Common side effects

  • Nausea
  • Hypotension
  • Dizziness
  • Pruritus

Counselling Points

  • Monitor for skin reactions.
  • Avoid use in pregnancy.
  • Transition to oral therapy as soon as possible.

Serious warnings

  • Increased cardiovascular risk
  • Gastrointestinal complications
  • Serious skin reactions
Important Disclaimer

The Raypare 40 mg Powder for solution for injection (powder for injection). professional information leaflet below is the property of Abex Pharmaceutica and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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