Raypare 40 mg Powder for solution for injection (powder for injection).
Clinical Summary
Quick overview from the medicine insert
Indication
Short-term management of post-operative pain.
Dosage (summary)
Initial 40 mg IV/IM, then 20-40 mg every 6-12 hours, max 80 mg/day.
Onset of Action / Duration
Onset: 7-14 mins, Duration: 7+ hours.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- Fluconazole
- Warfarin
- ACE inhibitors
- Diuretics
Contraindications
- Hypersensitivity to parecoxib
- Severe hepatic impairment
- Severe renal impairment
- History of gastrointestinal bleeding
- Coronary artery bypass surgery
Common side effects
- Nausea
- Hypotension
- Dizziness
- Pruritus
Counselling Points
- Monitor for skin reactions.
- Avoid use in pregnancy.
- Transition to oral therapy as soon as possible.
Serious warnings
- Increased cardiovascular risk
- Gastrointestinal complications
- Serious skin reactions
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