Rilutek Tablets 50 mg Tablets
PDF Leaflet Revision Date: 01.04.2022
Clinical Summary
Quick overview from the medicine insert
Indication
Extension of survival in bulbar variant of motor neuron disease.
Dosage (summary)
100 mg daily (50 mg every 12 hours), taken between meals.
Onset of Action / Duration
Onset: 60-90 mins, Duration: 9-15 hours
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- CYP 1A2 inhibitors (e.g., caffeine, diclofenac)
- CYP 1A2 inducers (e.g., rifampicin, omeprazole)
Contraindications
- Severe hypersensitivity to riluzole
- Hepatic disease
- Pregnancy
- Lactation
Common side effects
- Nausea
- Diarrhoea
- Headache
- Dizziness
- Increased ALT
Counselling Points
- Take between meals
- Report any febrile illness
- Avoid driving if experiencing dizziness
Serious warnings
- Risk of hepatitis
- Monitor ALT levels
- Dizziness may impair ability to drive
Important Disclaimer
The Rilutek Tablets 50 mg Tablets professional information leaflet below is the property of Sanofi-Aventis South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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