Seroquel XR 50mg. 150mg. 200mg. 300mg. 400mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of schizophrenia and bipolar disorder.
Dosage (summary)
Adults: Start at 300 mg, increase to 800 mg as needed. Elderly: Start at 50 mg, adjust as tolerated.
Onset of Action / Duration
Onset: 1-2 weeks, Duration: 24 hours
Special Populations
- Elderly
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated during pregnancy and lactation.
Key Drug Interactions
- CYP3A4 inhibitors
- Hepatic enzyme inducers
Contraindications
- Hypersensitivity to quetiapine
Common side effects
- Somnolence
- Dizziness
- Dry mouth
- Constipation
- Tachycardia
Counselling Points
- Monitor for signs of hyperglycaemia
- Avoid alcohol
- Gradual withdrawal recommended
Serious warnings
- Risk of hyperglycaemia
- Neuroleptic malignant syndrome
- QT prolongation
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