Spiractin 25 mg Tablets
PDF Leaflet Revision Date: 15 February 1979
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of oedema and ascites associated with hepatic cirrhosis.
Dosage (summary)
Initial 100 mg daily in 4 divided doses; may increase to 400 mg if necessary.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established.
Key Drug Interactions
- Enhances effects of antihypertensives
- Caution with other potassium-sparing agents
Contraindications
- Acute renal insufficiency
- Anuria
- Hyperkalaemia
Common side effects
- Hyperkalaemia
- Hyponatraemia
- Drowsiness
- Headache
- Ataxia
Counselling Points
- Avoid potassium supplements
- Monitor serum electrolytes
- Gradually decrease dose on discontinuation
Serious warnings
- Risk of hyperkalaemia
- Caution in severe hepatic disease
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