Thalidomide 50 Mg Bms 50 mg Hard capsules
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of multiple myeloma and erythema nodosum leprosum.
Dosage (summary)
200 mg daily for multiple myeloma; 400 mg daily for erythema nodosum leprosum.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; use effective contraception.
Key Drug Interactions
- Increased sedation with CNS depressants
- Caution with drugs causing bradycardia
- Increased risk of peripheral neuropathy with certain drugs
Contraindications
- Pregnancy
- Breastfeeding
- Hypersensitivity
- Women of childbearing potential without contraception
- Males not complying with contraceptive measures
Common side effects
- Neutropenia
- Somnolence
- Peripheral neuropathy
- Constipation
- Fatigue
Counselling Points
- Use two reliable forms of contraception
- Avoid driving if drowsy
- Report any signs of severe skin reactions
- Monitor for signs of thromboembolism
Serious warnings
- Teratogenic effects
- Risk of thromboembolic events
- Severe skin reactions
- Progressive multifocal leukoencephalopathy
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