Thimatrin 5 mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Management of hyperthyroidism and preparation for thyroidectomy.
Dosage (summary)
10 mg to 60 mg daily, titrated based on thyroid function.
Special Populations
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Use lowest effective dose in pregnancy; contraindicated in breastfeeding.
Key Drug Interactions
- Anticoagulants
- Theophylline
- Prednisolone
- Erythromycin
Contraindications
- Hypersensitivity to carbimazole
- Severe hepatic insufficiency
- Acute pancreatitis history
- Tracheal obstruction
Common side effects
- Nausea
- Headache
- Gastrointestinal disturbances
- Skin rashes
Counselling Points
- Monitor for sore throat, bruising, fever
- Avoid in acute pancreatitis history
- Regular blood counts recommended
Serious warnings
- Risk of agranulocytosis
- Bone marrow depression
- Acute pancreatitis
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