Neomercazole 5 mg Tablets
PDF Leaflet Revision Date: 25 September 2020
Clinical Summary
Quick overview from the medicine insert
Indication
Management of hyperthyroidism and preparation for thyroidectomy.
Dosage (summary)
10 mg to 60 mg daily, titrated based on thyroid function.
Special Populations
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; teratogenic effects noted.
Key Drug Interactions
- Anticoagulants
- Theophylline
- Iodine-containing medications
Contraindications
- Hypersensitivity to carbimazole
- Severe hepatic insufficiency
- Agranulocytosis
- Acute pancreatitis
Common side effects
- Agranulocytosis
- Nausea
- Headache
- Rash
Counselling Points
- Report signs of infection immediately
- Use effective contraception
- Avoid breastfeeding while on treatment
Serious warnings
- Risk of agranulocytosis
- Monitor liver function
- Caution in tracheal obstruction
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