Thymoglobuline 25 mg Powder for solution for infusion.
PDF Leaflet Revision Date: 15 April 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Immunosuppression in transplantation and severe aplastic anaemia.
Dosage (summary)
1-1.5 mg/kg/day for 2-9 days post-transplant; 2.5-3.5 mg/kg/day for 5 days in aplastic anaemia.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; discontinue breastfeeding during therapy.
Key Drug Interactions
- Ciclosporin
- Tacrolimus
- Mycophenolate mofetil
- Live attenuated vaccines
Contraindications
- Hypersensitivity to rabbit proteins
- Active infections
Common side effects
- Infection
- Lymphopenia
- Thrombocytopenia
- Hypotension
- Fever
Counselling Points
- Monitor for infusion reactions
- Avoid live vaccines
- Use under medical supervision
Serious warnings
- Anaphylaxis
- Cytokine release syndrome
- Infection risk
Important Disclaimer
The Thymoglobuline 25 mg Powder for solution for infusion. professional information leaflet below is the property of Sanofi-Aventis South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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