Trilef 400mg, 300 mg, 300 mg Tablet

Trilef 400mg, 300 mg, 300 mg Tablet

S4
PDF Leaflet Revision Date: 02 May 2023


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of HIV-1 in adults over 18 years.

Dosage (summary)

One tablet daily on an empty stomach; bedtime dosing recommended.

Special Populations

  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy and breastfeeding.

Key Drug Interactions

  • CYP450 inducers/inhibitors
  • St. John's wort
  • Terfenadine

Contraindications

  • Hypersensitivity
  • Severe hepatic impairment
  • Moderate to severe renal impairment
  • Pregnancy
  • Lactation

Common side effects

  • Dizziness
  • Nausea
  • Rash
  • Fatigue

Counselling Points

  • Take on an empty stomach
  • Monitor for liver function
  • Use barrier contraception

Serious warnings

  • Lactic acidosis
  • Severe hepatotoxicity
  • Immune reconstitution inflammatory syndrome
Important Disclaimer

The Trilef 400mg, 300 mg, 300 mg Tablet professional information leaflet below is the property of Cipla Medpro and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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