Trintogen 5/10/20 5 mg/ 10 mg/ 20 mg Tablet
PDF Leaflet Revision Date: 19 July 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of major depressive disorder and relapse prevention.
Dosage (summary)
Starting dose: 10 mg once daily; may adjust to 5-20 mg based on response.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Limited safety data in pregnancy; potential risks in newborns. Excreted in breast milk.
Key Drug Interactions
- Strong CYP2D6 inhibitors
- Broad CYP inducers
- Serotonergic medicines
Contraindications
- Hypersensitivity to vortioxetine
- Concomitant use with MAOIs
Common side effects
- Nausea
- Dizziness
- Constipation
- Abnormal dreams
Counselling Points
- Monitor for suicidal thoughts
- Avoid abrupt discontinuation
- Caution with alcohol
Serious warnings
- Risk of suicidal thoughts
- Serotonin syndrome
- Seizures
- Hyponatraemia
Important Disclaimer
The Trintogen 5/10/20 5 mg/ 10 mg/ 20 mg Tablet professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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