Wormadole 400mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Indicated for various cancers including breast, lung, ovarian, prostate, and head and neck cancers.
Dosage (summary)
Administered as an IV infusion; typical dose is 75-100 mg/mu00b2 every 3 weeks depending on cancer type.
Onset of Action / Duration
Onset: 30 mins, Duration: 6-8 hours
Special Populations
- Hepatic impairment
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation due to teratogenic effects.
Key Drug Interactions
- CYP3A4 inhibitors
- Doxorubicin
- Cisplatin
Contraindications
- Hypersensitivity to docetaxel
- Neutrophil count < 1500 cells/mmu00b3
- Severe liver impairment
Common side effects
- Neutropenia
- Alopecia
- Nausea
- Vomiting
- Stomatitis
Counselling Points
- Monitor for signs of infection
- Avoid pregnancy during treatment
- Hydration and anti-emetics may be necessary
Serious warnings
- Severe hypersensitivity reactions
- Fluid retention
- Increased risk of infection
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