Zaario 50 mg & 100 mg FC tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of hypertension and renal protection in type 2 diabetic patients with hypertension and proteinuria.
Dosage (summary)
50 mg once daily, may increase to 100 mg; consider 25 mg for volume-depleted patients.
Onset of Action / Duration
Onset: 3-6 weeks, Duration: 24 hours
Special Populations
- Elderly
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; not recommended during breastfeeding.
Key Drug Interactions
- Potassium-sparing diuretics
- Lithium
- NSAIDs
Contraindications
- Hypersensitivity to losartan
- Severe renal impairment
- Bilateral renal artery stenosis
- Pregnancy
Common side effects
- Dizziness
- Headache
- Fatigue
- Cough
- Hyperkalaemia
Counselling Points
- Monitor blood pressure regularly
- Avoid potassium supplements
- Discontinue if pregnancy is suspected
Serious warnings
- Angioedema
- Hypotension
- Renal impairment
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