Zalcaren 50 mg Injection

Zalcaren 50 mg Injection

S3
PDF Leaflet Revision Date: 13 May 2022


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of multiple myeloma and ovarian cancer.

Dosage (summary)

IV doses vary from 8 mg/mu00b2 to 200 mg/mu00b2, adjusted based on blood counts.

Special Populations

  • Renal impairment
  • Elderly
  • Children

Pregnancy & Breastfeeding

Contraindicated in pregnancy and breastfeeding.

Key Drug Interactions

  • Nalidixic acid
  • Ciclosporin
  • Live vaccines

Contraindications

  • Previous allergic reaction to melphalan
  • Pregnancy
  • Lactation
  • Live attenuated vaccines

Common side effects

  • Nausea
  • Vomiting
  • Thrombocytopenia
  • Neutropenia
  • Alopecia

Counselling Points

  • Avoid pregnancy during treatment
  • Monitor for signs of bleeding
  • Report any allergic reactions immediately

Serious warnings

  • Myelosuppression risk
  • Leukaemogenic potential
  • Cytotoxic handling precautions
Important Disclaimer

The Zalcaren 50 mg Injection professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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