Zanrit 300 mg & 100 mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 infection in combination with other antiretroviral medicines.
Dosage (summary)
One tablet daily with food.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Digoxin
- Amiodarone
- Rifampicin
- St. John's Wort
- Midazolam
- Triazolam
Contraindications
- Hypersensitivity to atazanavir or ritonavir
- Moderate to severe liver disease
- Co-administration with certain antiarrhythmics and ergot derivatives
Common side effects
- Nausea
- Diarrhea
- Jaundice
- Rash
Counselling Points
- Take with food to enhance absorption.
- Monitor for signs of liver dysfunction.
- Avoid alcohol and certain medications.
Serious warnings
- Risk of serious drug interactions
- Potential for liver toxicity
- Immune Reconstitution Inflammatory Syndrome (IRIS)
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