Zelivire 500 mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of herpes zoster and recurrent genital herpes.
Dosage (summary)
Herpes zoster: 1000 mg TID for 7 days; Recurrent genital herpes: 500 mg BID for 5 days.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established; avoid breastfeeding.
Key Drug Interactions
- Cimetidine
- Probenecid
- Mycophenolate mofetil
Contraindications
- Hypersensitivity to valaciclovir or aciclovir
Common side effects
- Headaches
- Nausea
- Fatigue
- Dizziness
Counselling Points
- Ensure adequate hydration
- Monitor for skin reactions
- Use safer sex practices
Serious warnings
- Risk of DRESS
- Thrombotic thrombocytopenic purpura
- Neurological effects in renal impairment
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