Zyprexa Im 10.0 mg Powder for solution for injection
Clinical Summary
Quick overview from the medicine insert
Indication
Control of agitation in schizophrenia and acute mania.
Dosage (summary)
10 mg IM, may repeat up to 30 mg/day; elderly: 2.5-5 mg.
Onset of Action / Duration
Onset: 15-45 mins, Duration: not specified
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not established; monitor newborns for withdrawal symptoms.
Key Drug Interactions
- Benzodiazepines
- CYP1A2 inhibitors
- Antihypertensives
Contraindications
- Hypersensitivity to olanzapine
- Narrow-angle glaucoma
Common side effects
- Somnolence
- Bradycardia
- Hypotension
Counselling Points
- Avoid alcohol
- Monitor for sedation
- Report any unusual symptoms
Serious warnings
- Risk of NMS
- Cerebrovascular events in elderly
- Discontinuation reactions
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