Zyprexa 2.5mg. 5mg. 10mg, 10mg Tablet, Injection

Zyprexa 2.5mg. 5mg. 10mg, 10mg Tablet, Injection

S5
PDF Leaflet Revision Date: 15 November 2010

API: Olanzapine | Company: Eli Lilly

Clinical Summary

Quick overview from the medicine insert

Indication

Management of psychotic disorders and acute mania.

Dosage (summary)

Initial dose 5-10 mg/day, target 10 mg/day; IM 10 mg as needed.

Onset of Action / Duration

Onset: 5-8 hours, Duration: 24 hours

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Safety not established during pregnancy and lactation.

Key Drug Interactions

  • CNS depressants
  • Levodopa
  • Antihypertensives

Contraindications

  • Hypersensitivity
  • Narrow-angle glaucoma

Common side effects

  • Weight gain
  • Somnolence
  • Orthostatic hypotension
  • Dry mouth

Counselling Points

  • Monitor for weight gain
  • Avoid alcohol
  • Caution with driving
  • Gradual discontinuation recommended

Serious warnings

  • Neuroleptic malignant syndrome
  • Seizures
  • Tardive dyskinesia
  • Hyperglycemia
Important Disclaimer

The Zyprexa 2.5mg. 5mg. 10mg, 10mg Tablet, Injection professional information leaflet below is the property of Eli Lilly and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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