Apize Tablets
PDF Leaflet Revision Date: 21 February 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of schizophrenia and acute manic episodes in Bipolar I disorder.
Dosage (summary)
Starting dose: 10-15 mg/day; Maintenance: 15 mg/day; Max: 30 mg/day.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; excreted in breast milk.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP2D6 inhibitors
- CYP3A4 inducers
Contraindications
- Hypersensitivity to aripiprazole
- Children under 18
Common side effects
- Akathisia
- Nausea
- Sedation
- Dizziness
Counselling Points
- Monitor for suicidal thoughts
- Avoid alcohol
- Caution with driving
Serious warnings
- Risk of suicide
- Neuroleptic Malignant Syndrome
- Tardive dyskinesia
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