Haemocarb Adco (Acid Concentrate). 4,0 mmol/l A clear, colourless solution. Water for injections
Clinical Summary
Quick overview from the medicine insert
Indication
Severe recalcitrant nodular acne.
Dosage (summary)
Start at 0.5 mg/kg daily; may increase to 2.0 mg/kg for severe cases.
Onset of Action / Duration
Onset: 2-4 hours, Duration: 16-24 weeks.
Special Populations
- Hepatic impairment
- Renal insufficiency
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; teratogenic effects.
Key Drug Interactions
- Avoid vitamin A
- Contraindicated with tetracyclines
Contraindications
- Pregnancy
- Lactation
- Hypersensitivity to isotretinoin
- Hypervitaminosis A
Common side effects
- Dry skin
- Cheilitis
- Headache
- Depression
- Increased triglycerides
Counselling Points
- Use effective contraception
- Avoid sun exposure
- Monitor for mood changes
- Do not share medication
Serious warnings
- Teratogenic risk
- Hepatitis
- Pseudotumour cerebri
- Severe skin reactions
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