Donecept 5, Donecept 10 5 mg,10 mg, Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Symptomatic treatment of mild to moderate dementia in Alzheimer's disease.
Dosage (summary)
Start with 5 mg/day in the evening, may increase to 10 mg/day after one month.
Onset of Action / Duration
Onset: 1 month, Duration: not specified
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy and lactation.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP2D6 inhibitors
- Anticholinergics
Contraindications
- Hypersensitivity to donepezil
- Pregnancy
- Lactation
- Children
Common side effects
- Nausea
- Diarrhoea
- Dizziness
- Fatigue
Counselling Points
- Take in the evening before bed
- Monitor for gastrointestinal symptoms
- Evaluate ability to drive or operate machinery
Serious warnings
- Bradycardia
- QTc prolongation
- Seizures
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