Prifet 5 Mg & 10 Mg Tablets 5 mg & 10 mg TABLET
PDF Leaflet Revision Date: 26 February 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Symptomatic treatment of mild to moderate dementia in Alzheimer's disease.
Dosage (summary)
5 mg once daily, may increase to 10 mg after 4-6 weeks.
Onset of Action / Duration
Onset: 3-4 hours, Duration: Steady-state in 3 weeks.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety not established; use with caution.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP2D6 inhibitors
- Anticholinergics
Contraindications
- Hypersensitivity to donepezil
- Children
Common side effects
- Diarrhoea
- Nausea
- Vomiting
- Dizziness
- Fatigue
Counselling Points
- Monitor weight
- Assess driving ability
- Report severe side effects
Serious warnings
- Monitor for therapeutic benefit
- Risk of bradycardia
- Potential for gastrointestinal bleeding
Important Disclaimer
The Prifet 5 Mg & 10 Mg Tablets 5 mg & 10 mg TABLET professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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