Rosuzet 5 Mg/10 Mg, Rosuzet 10 Mg/10 Mg, Rosuzet 20 Mg/10 Mg, Rosuzet 40 Mg/10 Mg 5 mg, 10 mg, 20 mg, 40 mg Tablet

Rosuzet 5 Mg/10 Mg, Rosuzet 10 Mg/10 Mg, Rosuzet 20 Mg/10 Mg, Rosuzet 40 Mg/10 Mg 5 mg, 10 mg, 20 mg, 40 mg Tablet

S4
PDF Leaflet Revision Date: TBA


Clinical Summary

Quick overview from the medicine insert

Indication

Adjunctive therapy for primary hypercholesterolemia and cardiovascular event prevention.

Dosage (summary)

One tablet daily; starting dose 10 mg rosuvastatin + 10 mg ezetimibe.

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy and breastfeeding; use effective contraception.

Key Drug Interactions

  • Gemfibrozil
  • Ciclosporin
  • Protease inhibitors

Contraindications

  • Hypersensitivity
  • Active liver disease
  • Severe renal impairment
  • Pregnancy and breastfeeding

Common side effects

  • Myalgia
  • Headache
  • Dizziness
  • Nausea

Counselling Points

  • Report unexplained muscle pain or weakness.
  • Monitor liver function tests.
  • Maintain a lipid-lowering diet.

Serious warnings

  • Risk of myopathy/rhabdomyolysis
  • Liver function monitoring required
  • Diabetes risk

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Rosuzet 5 Mg/10 Mg, Rosuzet 10 Mg/10 Mg, Rosuzet 20 Mg/10 Mg, Rosuzet 40 Mg/10 Mg 5 mg, 10 mg, 20 mg, 40 mg Tablet
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